Outbreak of Coronavirus

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ukimalefu
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Post by ukimalefu »

Merck says a trial shows it has produced the first effective antiviral pill for Covid.

The drug maker Merck said on Friday that it would seek authorization for the first antiviral pill for Covid after its drug, known as molnupiravir, was shown in a clinical trial to cut the risk of hospitalization or death in half when given to high-risk people early in their infections.

The Merck drug, which is designed to stop the coronavirus from replicating, is to be taken as four capsules twice a day for five days.

For the research, the monitors looked a ... e placebo.

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ukimalefu
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Post by ukimalefu »

Pandemic skyrockets in Europe; COVID is the No. 1 cause of death
"There is a duty to society to get vaccinated."

https://arstechnica.com/science/2021/11 ... -of-death/

"In many countries and communities, we're concerned about the false sense of security that vaccines have ended the pandemic and that people who are vaccinated do not need to take any other precautions," Dr. Tedros said. "Vaccines save lives, but they do not fully prevent transmission." Fully vaccinated people can still get breakthrough infections and spread the virus onward. And with continued transmission comes the continued risk that new variants will emerge.

"While Europe is again the epicenter of the pandemic, no country or region is out of the woods," Dr. Tedros warned.

-

Keep wearing your masks, don't touch your face, wash your hands, keep your distance

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Yori
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Post by Yori »

Someone at my office tested positive so I went for a PCR test today. I've done 2 lateral flow tests and they were negative so fingers crossed.

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TOS
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Post by TOS »

ontario is doing incredibly well right now with covid, around 90% vaccinated and kids about to get their shots

my question is how much that will really matter once they return to "normal" in the spring (the premier says all of it ends in march)

this bug is so damn aggressive

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ukimalefu
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Post by ukimalefu »

COVID-19: Most Omicron cases are 'mild' and there's no evidence to suggest vaccines may be less effective against the variant, says WHO official

The World Health Organisation has also urged countries to apply "an evidence-informed and risk-based approach" to travel measures, saying blanket bans will not prevent the spread of the new Omicron COVID variant.

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ukimalefu
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Post by ukimalefu »

After that news, I don't feel about posting a joke about it

The Omicron Variant sounds like a 60’s sci-fi movie

Image

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Séamas
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Post by Séamas »

One of the better movies featuring Harry Carey Jr. imho.

And Proteus brought the upright beast into the garden and chained him to a tree and the children did make sport of him.
DEyncourt
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Post by DEyncourt »

Dr. Steven Novella on omicron.

--

There something--a tweet?--in which Senator Ted Cruz wildly speculated about the HIDDEN REASONS why the WHO had entirely skipped nu and xi in its list of COVID variant names of concern or interest.

There were clear reasons why:

Nu was skipped to avoid the confusion among English speakers: "there is new concern about the nu variant."

Xi was avoided because that spelling in English is the same as the English spelling of the common Chinese surname Xi although they usually are pronounced differently.

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juice
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Post by juice »

I just assumed there were variants with that names but they hadn't become widespread.

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Post by DEyncourt »

"2nd US omicron case just traveled to NYC anime convention with 53K attendees".

The previously vaccinated Minnesota man had NOT traveled internationally but had attended the Anime NYC 2021 convention at the Javitz Center from November 19-21. He returned to Minnesota on Nov. 22 on which day he developed mild symptoms. On Nov. 24 he tested positve for COVID which later proved to be the omicron variant. He has since recovered from his illness.

According to the Anime NYC president this year's convention had "challenges with crowding".

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Séamas
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Post by Séamas »

DEyncourt wrote: Thu Dec 02, 2021 5:03 pm

"2nd US omicron case just traveled to NYC anime convention with 53K attendees".

The previously vaccinated Minnesota man had NOT traveled internationally but had attended the Anime NYC 2021 convention at the Javitz Center from November 19-21. He returned to Minnesota on Nov. 22 on which day he developed mild symptoms. On Nov. 24 he tested positve for COVID which later proved to be the omicron variant. He has since recovered from his illness.

According to the Anime NYC president this year's convention had "challenges with crowding".

I have heard people speak about "Con Crud" for years.

You would think with the history of people getting sick after conventions PLUS the pandemic, people would be that much more careful about social distancing.

And Proteus brought the upright beast into the garden and chained him to a tree and the children did make sport of him.
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Post by DEyncourt »

NY State has begun a program using the contact info gathered by that anime convention's organizer to contact everyone who attended to get a COVID test immediately and to urge them to personally isolate until they know they aren't positive. This is regardless of having been vaccinated because omicron variant may be only partially covered by current vaccines.

The governor announced that there are already 5 cases of omicron in NY. These were not necessarily connected to that anime convention.

--

On top of the previous reported cases in CA, NY and MN, you can add cases in HI and CO.

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obvs
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Post by obvs »

Yeah, I know.

Image

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ukimalefu
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Post by ukimalefu »

Image

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obvs
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Post by obvs »

Well that's a wasteful infographic made by someone who doesn't understand colorblindness at all...

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ukimalefu
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Post by ukimalefu »

obvs wrote: Mon Dec 06, 2021 9:27 am

Well that's a wasteful infographic made by someone who doesn't understand colorblindness at all...

Most of Europe is doing really good

The US is not as bad as I expected with all those deniers. I was going to change the colors in photoshop, but I don't really know what you need (what about your "magic glasses"?). Uhm... darker is better

Image

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obvs
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Post by obvs »

I do have magic glasses, but they're not handy right now. They're sunglasses, so I don't have them on all of the time.

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TOS
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Post by TOS »

i'm quite surprised that germany is so low

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Yori
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Post by Yori »

Covid: New Plan B rules on working from home and masks announced for England

People in England are being asked to work from home again if possible and face masks will be compulsory in most public places, as part of new rules to limit the spread of Omicron.

Vaccine passports will also be needed to get into nightclubs and large venues from next week.

Boris Johnson announced the government was moving to its back-up plan of extra Covid rules at a news conference.

"It's not a lockdown, it's Plan B," the prime minister said.

He said moving to the tougher measures was the "proportionate and responsible" thing to do.

Mr Johnson said more is still being learned about new variant Omicron and the picture might get better, but that it "could lead to a big rise in hospitalisations and therefore sadly in deaths".

He said the new variant was "growing much faster" than Delta and early analysis suggested cases could be doubling every 2.5 to three days.

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maurvir
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Post by maurvir »

COVID vaccines: Free

2 months of intubation in an ICU:
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juice
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Post by juice »

Is that 3.383 MILLION DOLLARS?

This system is so stick fiddled.

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TOS
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Post by TOS »

looks like omicron might not be the innocent lamb we thought it was

south africa has a much younger population and a higher level of immunity ... we (at least here in ontario) are at much higher risk

the best thing is to have three vaccine doses; the next best thing is two doses plus having had covid and recovered for it

"TOS ain’t havin no horserace round here. “Policies” is the coin of the realm." -- iDaemon
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ukimalefu
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Post by ukimalefu »

FDA authorizes first COVID-19 antiviral pill

On Wednesday, the Food and Drug Administration authorized the first antiviral pill to treat COVID-19, a move that gives doctors another tool to fight the disease. The treatment, made by Pfizer, curbs the risk of hospitalization and death in high-risk patients infected with the coronavirus.

The drug is authorized for people 12 years of age and older who are at a high risk of getting seriously ill if they contract the virus.

Called Paxlovid, the treatment includes 30 pills taken at home over five days. It has to be started within a few days of symptoms — which could be a challenge in the United States, where it may be difficult for many people to get a COVID-19 test, a result, and see a doctor for a prescription in that window.]FDA authorizes first COVID-19 antiviral pill

more sources:

https://www.npr.org/sections/health-sho ... -for-covid

https://abcnews.go.com/Health/pfizer-co ... d=81894094

The U.S. government has already contracted with Pfizer to purchase at least 10 million courses by the end of next year at $530 a course.

There is not expected to be any direct cost to patients.

course? well, no direct cost to patients? that's good right? good for them, not sure if the US government or insurance companies pay for it.

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Post by DEyncourt »

On her show last night Rachel Maddow also highlighted this story, but she emphasized that Pfizer can produce enough dosages of Paxlovid to cover only about 180,000 cases (a course of 45 pills to be taken 3 pills with each meal over 5 days) by the end of December. AND that Paxlovid has serious complications with several drugs that many Americans are currently taking daily, and for patients with liver and kidney problems (so folks like me who are undergoing dialysis probably should not take Paxlovid).

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Post by DEyncourt »

Scented Christmas candles are getting low scores again this year.

You may think "why here?", but while such low scores for scented candles were not unknown before 2020, they spiked last year and are doing so again this year. What wasn't well known in 2020 was how one of the symptoms of COVID and long COVID is reduced if not complete loss of being able to smell.

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Post by DEyncourt »

On her show tonight Rachel Maddow showed this graphic:

Image

which shows whether or not a given treatment could be applied to people who have the omicron variant. Forgive that show's choice of colors, but just know that the Lily and Regeneron monoclonal antibody treatments CANNOT be used for omicron cases.

Maddow was also speaking to a doctor about the availability and effectiveness of the various treatments. As I wrote before: the Pfizer pill treatment has only limited availabity and has some significant limitations, but Maddow also pointed out that while there are already millions of Merck dosages available, those pills have more severe restrictions upon who can take them and are only about 50% effective (as opposed to the 90% effectiveness of the Pfizer pill). Both pills also have a small time window for best effectiveness: within 3 to 5 days of first signs of infection by COVID.

The GlaxoSmithKline monoclonal antibody treatment has VERY limited availabiltiy, something in the rage of 200,000 treatments.

The AstraZeneca monoclonal treatment is new for the US so the US will have to compete with European countries which had previously approved it.

--

So we in the US are looking towards probably getting everyone who isn't already partially vaccinated to get the omicron variant, so some 60-90 M Americans (that wide window is complicated by how there are some people who cannot get vaccinated because they are too young or are immuno-compromised). Based on current numbers of deaths over number of cases which is now 1.5% deaths for new cases, that might mean between 950,000 to 1,400,000 additional deaths before we're done. This is on top of the current 812 K deaths.

At between 1.7 and 2.2 M dead Americans we will exceed the number who died from the 1918 Spanish Flu (between 500 and 800 K deaths), but in 1918 the US had less than 1/3rd its current population so in terms of percentage will likely will approach those numbers. Of course I've based my projections on the death rate mostly for the delta variant. Given that some assume that the death rate for the omicron variant might be less, so my projections might be an overestimate.

This is not to say that the vaccinated will get through scotfree. They and those previously infected with COVID are likely to get some omicron infections, but their rates of serious infections requiring hospitalization and thus their rates of death are drasically less than for the unvaccinated.

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Post by DEyncourt »

"Nearly 5,000 flights canceled as omicron helps spark Christmas travel chaos".

Mind you: nearly all of these flight cancellations were due to the AIRLINES lacking enough personnel due to possible omicron infections.

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TOS
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Post by TOS »

so the cdc shortened its recommended quarantine to five days

not because of medical data, but because it was annoying too many people

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Post by DEyncourt »

89 different cruise ships have reported at least one case of COVID.

Several of these ships could not dock at planned ports due to their COVID (bets on how many will try to NOT report on their COVID cases?).

There are calls demanding that public officials put a pause upon all further cruising.

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Post by ukimalefu »

Texas Scientists Are Sharing the Design for Their New, Cheap Covid-19 Vaccine

On Tuesday, Indian health regulators granted an emergency use authorization to the Corbevax vaccine, created by scientists from the Texas Children’s Hospital Center for Vaccine Development at Baylor College of Medicine. The vaccine was further developed and tested in partnership with the Indian pharmaceutical company Biological E, which will handle the local production of the vaccine. Clinical trials have shown that Corbevax is safe and estimates indicate that it’s more than 90% effective against the original form of the coronavirus, as well as more than 80% effective against the Delta variant.

...it can be easily and cheaply scaled up, even in countries with limited resources. Importantly, it can be stored using standard refrigeration, which would allow for more widespread transportation and use than the mRNA vaccines that require special refrigeration.

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TOS
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Post by TOS »

DEyncourt wrote: Wed Dec 29, 2021 4:14 pm

89 different cruise ships have reported at least one case of COVID.

Several of these ships could not dock at planned ports due to their COVID (bets on how many will try to NOT report on their COVID cases?).

There are calls demanding that public officials put a pause upon all further cruising.

i've said it before and i'll say it again

how

the

fiddlesticks

can

people

be

fiddlesticks

cruising

right

now

"TOS ain’t havin no horserace round here. “Policies” is the coin of the realm." -- iDaemon
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Post by macnuke »

You’d understand if you were a lifelong Republican

People that do not succeed in politics usually tell the truth too often.

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maurvir
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Post by maurvir »

macnuke wrote: Sat Jan 01, 2022 9:21 pm

You’d understand if you were a lifelong Republican

This

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Post by Metacell »

Cruise ships are one of the weapons in their war against nature and all life on Earth.

Remember, people, to forgive is divine. In other words, it ain't human.
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Post by justine »

So, we voluntarily test once a week. 2 groups. The weekends and monday people, andThursday, everyone else. At this point, testing is voluntary. From last Mondays group, 20 people tested positive. I'm guessing about 30% of those that tested. I go in tonight so i'll see if there's any changes.

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maurvir
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Post by maurvir »

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obvs
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Post by obvs »

He looks like someone who drinks urine.

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juice
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Post by juice »

Why isn't he selling urine as a cure? He's missing a business opportunity here, unless he's monetizing his advice in another way.

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